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Exosomal-miR-129-2-3p derived from Fusobacterium nucleatum -infected intestinal epithelial cells promotes experimental colitis through regulating TIMELESS-mediated cellular senescence pathway

Disulfiram (DSF), an FDA-approved drug for chronic alcoholism, has shown potent anti-tumor effect, particularly when used in combination with copper (Cu)

Opdam S, Richelle A, Kellman B, Li S, Zielinski DC, Lewis NE

FEBS J (2016) 283:37894

A notable example includes the co-delivery of resveratrol and paclitaxel via PEGylated liposomes, which exhibited potent cytotoxicity against drug-resistant breast cancer cells (MCF-7/Adr) in vitro and enhanced tumor retention in vivo without increasing systemic toxicity