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However, subacute toxicity studies suggested that glycoalkaloids lacking metal ion conjugation contributed to increased toxicity

Specifically, these GSTs bind both the substrate and GSH at different sites of the enzyme, eventually activating the thiol group of GSH to enable nucleophilic attack on the substrate

The category Other for CV inclusion criteria includes patients where it is unknown if the patient fulfilled only one or several criteria and patients who were randomized in error and did not fulfill any criteria

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