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As the most representative carcinogen in PAHs [8, 42, 124], BaP contributed to breast cancer occurrence by changing tumor suppressor genes methylation

These reactions are triggered by the oxidative stress (OS) that occurs in the body

Periodontitis induces glutathione metabolic reprogramming in BM neutrophils To investigate how periodontitis alters GSH metabolism in BM neutrophils, we conducted an integrated analysis of transcriptomic and metabolomic datasets from Con and Lig mice

Furthermore, the non-invasive measures of LC, such as serological markers of type-III collagen turnover, improved at day 90

This is caused by an imbalance between factors that relax the endothelium, such as nitric oxide (NO), prostacyclin (PGI 2 ), and down regulation of endothelioum-dependent hyperpolarization (EDH) and factors that cause contraction such as thromboxane A 2 (TxA 2 ) and upregulation of endothelin-1 (ET-1)

The folate-MTHFR-SAM axis supplies the methyl donor required by DNMTs