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Contact your GP for B12 testing if you have: Symptoms suggesting deficiency (persistent fatigue, pins and needles, memory problems, glossitis) Risk factors for deficiency (vegan diet, gastric surgery, long-term metformin or proton pump inhibitor use) [1] [4] Concerns about whether your current supplementation dose is appropriate Underlying conditions affecting B12 metabolism (kidney disease, liver disease) Unexplained high B12 levels on a blood test when not taking supplements Routine monitoring is essential for patients receiving therapeutic B12 injections
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Plasma levels of liver enzymes (ALT, AST, ALP), and triglycerides all decreased, and MRI showed decrease hepatic steatosis

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Taken together, the results of this study imply that ALA may be a promising dietary supplement for reversing the pro-oxidant state linked to stroke

doi: 10.1038/s41598-020-71847-5, PMID: [DOI] [PMC free article] [PubMed] [Google Scholar] 147
