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If symptoms have been present for an extended period before treatment began, theres a possibility that some of the nerve damage could be irreversible

Acute copper toxicity from that level of exposure is not a realistic concern given how far it sits below established safe intake thresholds

Additionally, treatment of DIO mice with the NNMT inhibitor resulted in a substantial 35% decrease (P 30% decrease in adipocyte size (P 40% decrease in adipocyte volume (data not shown) compared to control DIO mice

B vitamins are essential for the body to function properly

These are population-level results across a large, diverse trial cohort

These include the patients health history, how bad the B12 deficiency is, and how they react to the first treatment