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Therapy takes place in two phases: 1

On the other end of the spectrum, spacing doses too far apart, such as every 1014 days, can create a different issue

This approach extends the titration timeline significantly but can make the difference between tolerating the medication and quitting

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A deficiency in Vitamin B12 can cause fatigue and sluggishness, so supplementing with B12 can help increase energy and combat tiredness, which is particularly useful for those on calorie-restricted diets

Pasut G, Veronese F (2007) Polymerdrug conjugation, recent achievements and general strategies
