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doi: 10.1523/JNEUROSCI.22-02-00486.2002

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The expression of CXCL5 in PanIN-2 and PanIN-3 was significantly higher than that of PanIN-1, indicating that CXCL5 gradually increased in the progression of precancerous PanIN lesions to invasive cancer

(4) Melanotan II and Arousal Regulation via the MC4R The MC4Rs are another group of melanocortin receptors localized in the central nervous system, most likely in the hypothalamus