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662 Daminozide and siRNA can similarly downregulate KDM7 expression and then regulate tumor-repopulating cells via demethylation of H3K9
In addition, increased formation of extracellular superoxide and hydrogen peroxide occurs during immune responses
High doses of caffeine can lead to increased production of reactive oxygen species (ROS), which are harmful free radicals

J Trace Elem Med Biol (2018) 50:498507
Chen M, Wei L, Law CT, Tsang FH, Shen J, Cheng CL, et al
