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Published research has quantified this effect directly: at concentrations of 12 M, only 1020% of expected peptide content was recovered from standard borosilicate glass vials and polypropylene tubes after incubation, while low-binding tubes showed significantly better recovery

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However, to fully realize the therapeutic potential of the ENS, ongoing clinical trials, long-term follow-up studies, and interdisciplinary collaboration are necessary to address the remaining scientific and clinical challenges

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