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Both experienced increased heart rate, trouble breathing, and swollen tongues

The effect was due to accelerated angiogenesis but not vasodilation, since there was no significant difference of the blood flow in tails and non-ischemic hind limb between the control and BPC 157 groups

Also diarrhoea, peripheral vascular thrombosis, transitory exanthema, or urticaria

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doi: 10.1097/BCR.0b013e318240540a

But they came from a single research group, conducted in a single country, with limited independent replication a well-documented limitation in this literature