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Detection of ADA against therapeutic mAbs is highly challenging since both the drug and the analyte are antibodies

Fungal Genet Biol 49:302312 Drakulic T, Temple MD, Guido R, Jarolim S, Breitenbach M, Attfield PV, Dawes IW (2005) Involvement of oxidative stress response genes in redox homeostasis, the level of reactive oxidative species, and ageing in Saccharomyces cerevisiae
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Int J Mol Med (2016) 38(1):33744

Despite these advances, challenges such as poor bioavailability and limited clinical validation remain major barriers to translation

Glutathione Reductase (GR) The higher specific activity of GR in MASH114 might have caused early activation of GR in MASH114 at 20 DAS which might be responsible for providing resistance against the YMD in the kharif season (Fig
