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The results confirmed that Tbx1 +/ and Df1 / + brains have increased concentrations of MMA compared with WT controls (all animals were PBS-treated), and they showed that although vB12 treatment had no impact on MMA in WT animals, it was restored to WT levels in both of these mutants (Fig 3)

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This fragment was first isolated and studied in the 1980s and 1990s by researchers investigating which portions of the growth hormone molecule were associated with different structural domains