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It is one of the leading causes of fetal, neonatal and perinatal mortality and morbidity

10.1007/s00726-006-0396-9 Amino Acids 13 FaggianoA.MelisD.AlfieriR.De MartinoM.FilippellaM.MiloneF.et al (2005)

Two main techniques are used

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doi: 10.3389/fmicb.2011.00117 63 CoureuilM.JametA.BilleE.LcuyerH.BourdoulousS.NassifX