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Cancer Cell Int Metabolomics reveals ascorbic acid inhibits ferroptosis in hepatocytes and boosts the effectiveness of anti-PD1 immunotherapy in hepatocellular carcinoma

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Tight junctions mainly comprise of proteins like occludins and claudins (Luissint et al., 2012)

Thus, lactic acid constitutes a crucial part of a signaling cascade that allows optimal partitioning of glucose metabolism intermediates for energetics and reductive biosynthetic and anti-oxidation capabilities, and in so doing plays essential roles during malignancy of solid tumors

Gene-level expression quantification was performed using Salmon v1.10.1 in quasi-mapping mode 61

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