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High-affinity SOAT1 ligands remodeled cholesterol metabolism program to inhibit tumor growth

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IGF-1 has been shown to stimulate glucose transport into muscle via IGF-1 receptors or insulin/IGF-1 hybrid receptors, and a high concentration of free IGF-1 has been shown to suppress gluconeogenesis in mice directly (109111)

Serum insulin-like growth factor (IGF)-I and IGF-binding protein-3 concentrations and prostate cancer risk: Results from the European Prospective Investigation into Cancer and Nutrition

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This review summarizes the state of the science regarding new mechanism of dynamic control within the ovary in which IGFs can be a pivotal message and granulosa cell as their place to produce, receive, and act