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In addition, we explored the current challenges and strategies associated with LNPs for in-vivo RNA delivery, such as ensuring repeated-dose efficacy, safety, and tissue-specific gene delivery

Int J Mol Sci 22:1 [DOI] [PMC free article] [PubMed] [Google Scholar] 43.Germain A, Ruppert D, Levine SM, Hanson MR (2017) Metabolic profiling of a myalgic encephalomyelitis/chronic fatigue syndrome discovery cohort reveals disturbances in fatty acid and lipid metabolism