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Roccatello D, Fenoglio R, Sciascia S, Naretto C, Rossi D, Ferro M, et al

It is sold as a research chemical NNMT inhibition has broad implications : NNMT is involved in multiple metabolic pathways beyond NAD+, including methylation balance, polyamine metabolism, and one-carbon metabolism

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Pediatr Radiol 1997;27:1558

The reaction mixture was incubated in the dark or by illumination with a 530 nm LED for 3 min at 30 C, prior to the addition of GTP to initiate the reaction

The authors noted NNMT overexpression in many human malignancies and described 5-Amino-1MQ as a novel NNMT inhibitor with promising results across obesity and cancer cell research models