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Numerous studies have proposed that GHK-Cu acts as a potential SIRT1 activator, thereby highlighting its multifaceted role in cellular processes, especially its capacity to enhance SIRT1 activity ( in vivo and in vitro experiments

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The tight coordination of mitobiogenesis and mitophagy allows cells to adjust their mitochondrial content in response to physiological demands, stress, and other intracellular or environmental stimuli, such as cold, hypoxia, and nutrient supply

As a result, MET may be pivotal in the initial development of a tumour, as well as in its progression and ability to persist through cytotoxic treatment