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Tirzepatide (SURPASS trials): Weight reduction: 1521% depending on dose (515mg/week) Approved for type 2 diabetes Tolerability: mild to moderate GI effects Retatrutide (Phase 2 data): Weight reduction: 1724.2% across 1236 week protocols (515mg/week) Investigational

[DOI] [PMC free article] [PubMed] [Google Scholar] 31.Handa J.T