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Symptoms associated with vitamin B12 deficiency include fatigue and lack of energy (due to anemia), and depression, psychosis and even dementia

If clumps remain, brief bursts in a sonicator bath with cooling intervals can help

Other small molecule inhibitors have also been reported, including those derived from amino adenosine and other nicotinamide-related compounds 206208

This injectable medication works by mimicking the action of a naturally occurring hormone in the body called glucagon-like peptide-1 (GLP-1)

The dose of vitamin B12 injection for adults may vary depending on the problem to be treated: Treatment of mild nerve pain : the initial dose is 5,000 IU until pain resolves Treatment of intense nerve pain: the initial dose can be increased to 15,000 IU per day and reduced by the doctor as pain resolves Treatment of pernicious anemia: the dose can vary from 100 to 1000 IU per day and the treatment time varies from person to person

No delayed-onset adverse effects emerged that were not apparent in the initial weeks of treatment