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Choline a nutrient that controls cholesterol levels and helps the liver excrete waste products
Simons et al., 2005)
More efficient ATP production results in greater motility of sperm and greater developmental competence in eggs
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Conversely, pharmacologic inhibition of GSK3 (using 1-azakenpaullone) increased supporting cell proliferation in a -catenin dependent manner, indicating that the effects are mediated by canonical Wnt signaling
Bisubstrate strategies to target methyltransferases
