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The GIP receptor activation in tirzepatide appears to moderate the gastrointestinal effects of GLP-1 receptor activation

Furthermore, significant changes have been observed in the content of various proteins involved in mitophagy, mitochondrial dynamics, and mitochondrial biogenesis (Quinn et al., 2020)

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Effects of intranasal insulin as an enhancer of fear extinction: A randomized, double-blind, placebo-controlled experimental study