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Comparing AOD 9604 and tirzepatide weight loss outcomes requires acknowledging that these compounds were tested under different conditions, for different durations, and with different outcome measures
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* Leucine at a concentration of 0.5mM was shown to decrease the kM of NAD by 50% With Leucine, LESS NAD+ is needed for SIRT-1 functions, improving NAD+ utilization in other cellular pathways
