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Depletion of arginine results in reduced expression of CD3, an essential part of the T cell receptor (TCR) complex, ultimately impairing T cell activation [54, 55]

doi: 10.1111/j.1468-3083.2008.02681.x 87 Durham-PierreDGWaltersCSHalderRMPhamHNVanderpoolEA

The Dependence on ROS for the Survival and Malignant Progression in TNBC Otto Warburg was the first to describe a propensity for cancer cells to metabolize glucose anaerobically even in the presence of oxygen (the Warburg effect), and suggested an explanation for this abnormal glucose metabolism in terms of impaired bioenergetic activity of the mitochondria [94]

Life span extension by targeting a link between metabolism and histone acetylation in Drosophila

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The reductive potential of NADPH is maintained by glucose-6-phosphate dehydrogenase in the pentose phosphate pathway [26]
