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This was accompanied by adverse transcriptional changes in OmWAT and ScWAT including increased FA synthesis and inflammation
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These in vitro findings highlight that even within the same class of drugs, subtle differences in how they interact with their target receptors can exist, which may translate to different overall effects in the body

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It is noteworthy that these six new small-molecule peptidic metabolites were similarly detected in the urine, bile, fecal, and plasma samples

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